Thomas Richard Meux was born in 1838 in Wesley, Haywood County, Tennessee, the son of John Oliver Meux and Anne Tuggle Meux.
Thomas Meux attended the University of Virginia and graduated from the University of Pennsylvania Medical School in 1860 at the age of twenty-two.
In 1861, Dr. Meux enlisted as a private in the Ninth Tennessee Volunteer Regiment, Co. C, Maney's Co. Cheatham Division of the Confederate Army during the Civil War. He was at the battles of Shiloh, Murfeesborough and Atlanta. After four years as an assistant surgeon, he left the service as an assistant surgeon with the rank of Captain in 1865.
On June 3, 1874 he married Mary Ester Davis in Brownsville, Haywood County, Tennessee. They became the parents of John W., Mary D., and Anne Prenetta. Mrs. Meux was in poor health and on the advice of a brother, John P. Meux, who had moved to San Francisco in 1879, Dr. Meux decided to move his family to the Central Valley. In December, 1887, the Meux family registered at the Southern Pacific Hotel in Fresno.
Property in a prime residential area of the city, at the corner of Tulare and R Streets, was purchased by the doctor from the County of Fresno as a homesite in March, 1888, and the family moved into the house January, 1889.
Dr. Meux established his medical practice in 1889 and served the community as a physician until his retirement. He served as president of the Fresno County Medical Society in 1896 and was described as a staunch member of the Fresno County democratic Club and the Methodist Episcopal Church South. Thomas Meux and his brother, John, owned vineyards in the county and he maintained an active interest in agricultural affairs.

The Meux house was continuously occupied by the Meux family for a total of 81 years. Dr. Meux died at the age of 91 in 1929 and his daughter, Anne Prenetta Meux, died in 1970, having lived in the house since she was four years old.
The Fresno Bee (daily newspaper) heralded this occupancy as establishing the longest individual residence of one of Fresno's oldest wellings.
The Meux Home Museum is a tribute to the beauty of Victorian architecture. This magnificent two-story edifice has artfully composed roofs that thrust skyward from the second story, as do the numerous chimneys. The exterior walls are covered with a variety of textures and decorations including clapboards, shingles, and ornamental floral-like relief work. The large porch is held up by beautifully turned spindles accented with 'gingerbread', and designed to provide protection from the hot valley sun. The architecture blends all these beautiful features resulting in an intriguing historic home that invites visitors of all ages to enjoy its beauty and charm. It was placed on the National Register of Historic Places on January 14, 1975.

The Meux Home Museum recaptures the flavor of Victorian Fresno by presenting a middle-class residence furnished in the period, as a representative house museum. docentA costumed docent will lead you on a one hour tour of this restored urban dwelling of the 1890's. By modern standards elaborate, the Meux Home was nonetheless a middle-class residence, built for $12,000 from a carpenter's catalog. This home is typical of the Victorian Era it was created for. At that time the architecture took on a variety of forms from different sources that were brought together in a single design. All of this was done in order to create something charming and comfortable. To the Victorian, charm had to hold a certain element of surprise and this solid, two-story edifice has many such surprises. The silhouette of the Meux Home moves in and out at odd angles. A set of artfully composed roofs thrust skyward from the second story, as do the numerous chimneys. The walls of the home are covered with a variety of textures and decoration: horizontal clapboards, fish scale shingles, variegated shingles, and ornamental floral-like relief work. The large, roofed verandah which extends along the south and east walls is held up by beautifully turned spindle work accented with gingerbread details. The wide verandah offered relief and protection from the hot valley sun. The structure is filled with windows, complimented with individual sets of bat-wing shutters. One of its more interesting features is its octagonal shaped master bed-room with its steep, turreted roof. The architecture of the Meux Home results in a calculated restlessness that makes the home as intriguing today as it was in its own day. The 10 rooms are furnished more or less as a Victorian family might have had them - the kitchen has a pie safe and the library; a portrait showing the young Dr. Meux on his way to join the Confederate Army. The Meux home was placed on the National Register of Historic Places on January 14, 1975.